Education

        Thesis: Multi-scale Modeling of Chromatin during the Cell Cycle.
        Advisor: Jean-Marc Victor        Manuscript in French

  •  2001  M.S. Physics

    Pierre & Marie Curie University, Paris, France

        Modeling, Dynamics and Statistics of Complex Systems.

Research Experience

  • Since 2008, Research Associate

    Computer Lab, Cambridge University, Cambridge, UK

  • 2001, Master Degree

    LadHyX, Ecole polythechnique, Palaiseau, France

Publications 

My publications in PubMed

 
    Revaud D, Mozziconacci J, Sabatier L, Desmaze C, Lavelle C. 
    CELL CYCLE. 2009 Apr 4;8(7)


7. Tubulin dimers oligomerize before their incorporation into microtubules
   Mozziconacci J, Sandblad L, Wachsmuth M, Brunner D and Karsenti E.
   PLoS ONE 3(11): e3821. doi:10.1371/journal.pone.0003821(2008)
 
   PLoS ONE 2(9): e877. doi:10.1371/journal.pone.0000877 (2007)
   Discussed in the May 2008 issue of Chemistry world: "pulling our strings".
 
5. Nucleosome chiral transition under positive torsional stress in single chromatin fibers.
   Bancaud A, Wagner G, Conde E Silva N, Lavelle C, Wong H, Mozziconacci J, Barbi M, Sivolob A,  Le Cam   E, Mouawad L, Viovy JL, Victor JM, Prunell A.
   MOLECULAR CELL 27(1):135-47. (2007)
 
4. Torsional manipulation of single chromatin fibers reveals a highly flexible structure.
   Bancaud A, Cond e Silva N, Barbi M, Allemand JF, Mozziconacci J, Lavelle C, Croquette V, Victor JM,
   Prunell A, Viovy JL.
   NATURE STRUCTURAL AND MOLECULAR BIOLOGY 13(5):444-50. (2006)
 
3. A physical model for the condensation and decondensation of eukaryotic chromosomes.
   Mozziconacci J, Lavelle C, Barbi M, Lesne A, Victor JM.
  FEBS LETTERS 580(2):368-72.(2006).
 
2. How the chromatin fiber deals with topological constraints.
   Barbi M, Mozziconacci J and Victor JM.
   PHYSICAL REVIEW E 71 (3 Pt 1):031910 (2005).
   Presented in Nature ”News and views” Vol. 429
   and in the American Mathematical Society Maths in the Media.
   Selected for the April 1, 2005 issue of Virtual Journal of Biological Physics Research.
 
1. Nucleosome gaping supports a functional structure for the 30 nm chromatin fiber.
   Mozziconacci J, Victor JM.
   JOURNAL OF STRUCTURAL BIOLOGY 148 72–76 (2003).
 

Conference abstracts

 All-atom model of the chromatin fiber : a versatile structure tuned by the repeat length
 Mozziconacci  J., Wong  H. and  Victor J.M.
  FEBS JOURNAL   Volume: 274   Pages: 78   ( 2007)

 
 Chromatin structure and macromolecular confinement.
 Bancaud A, Daigle N,Mozziconacci J and Ellenberg J.
 BIOPHYSICAL JOURNAL 14A Suppl (2007)
 
 
 
Research Interests
 
Work in progress


Invited talks

 

  • Birmingham University, Birmingham, England, July 2008
  • Institut Jaques Monod, Paris, Fance, 2003

 

International Conferences

        Contributed poster, “Modeling the chromatin fiber from EM-imaging.”
        Contributed poster, “All-atom structure of the chromatin fiber.”
        Contributed talk, “How does the chromatin fiber deals with topological constraints.”
  • 13th Meeting of the Molecular Modeling and Visualization Group. Cabourg, France, 2003.
         Contributed talk, “Nucleosome gaping supports a functional structure for the 30 nm chromatin fiber.”   

Schools

  •   Comparative genomics of vertebrates: concepts and bio-informatics tools. La Londe-Les-Maures, France, 2004.
        Contributed poster, “A physical model for the compaction of the mitotic chromosome”
        Contributed talk, “How does the chromatin fiber deals with topological constraints.”
  • Understanding Molecular Simulation. Amesterdam, Netherlands, 2002.
  

Teaching experience

  •  Teaching in High School : Physics and Chemistry at the Carnot high school in Paris, May and June 2002.

 
Awards

  •  Prix "La Recherche" : J.M. Victor’s group was selected by the jury for great quality and innovative interdisciplinary work, 2006.

Computational Skills

  Image processing and analysis : JAVA based ImageJ tool.
 
  Programing languages : Perl, Python, C, C++, Matlab, Maple.
   
  Molecular Modeling : Molecular visualization program (VMD), Parallel molecular dynamics (NAMD), Parallelized  implementation of Density Functional Theory (CPMD).
   
  3D Modeling and Simulation : 3D animation program (Blender).


References
  • Jean Marc Victor: victor@lptl.jussieu.fr
  •  Pietro Lio': pl219@cam.ac.uk